Megamod - Fatal Access Violation - Setsprite?

[Vrayna]

If you're crashing when saving, you have to dig in your antivirus and check that it's not flagging Banished as unsafe or restricting its access to your Documents folder. Some super strict setups of Windows Defender can mess up with Banished. BitDefender is also sadly famous for its hatred of the game.
(I use Avira myself and never had issues with it, so I can't really healp much with the details of where to dig to find the correct options)